Anti-Aging

AOD9604 is a peptide fragment. It was specifically developed as an anti-obesity drug that prevents fat accumulation and boosts metabolism. It is an FDA-approved peptide that has the fat burning effects of human growth hormone. This is accomplished by stimulating lypolysis (fat breakdown) and inhibiting lipogenesis (fat formation). It tends to be most effective in the fat accumulation in the midsection. Its positive effects also include promoting the repair of bone and cartilage in cases of osteoarthritis. It is usually injected five out of seven days a week.

BPC 157 is a peptide found in gastric juices in the stomach. Because of its natural tendency to withstand enzyme destruction in the gastric juices, BPC 157 heals gastric ulcers and other wounds such as skin, corneal, muscle, and other digestive problems. BPC 157 is in clinical trials as a treatment for inflammatory bowel disease.

BPC 157 also shows promise in promoting collagen production. It also repairs ligament and tendon damage by increasing blood flow and decreasing inflammation. While scientists delve into it for other uses, researchers have suggested that BPC 157 has shown its influence on growth factors. The outcome of this influence is increasing blood flow and the regeneration of blood vessels. Overall, it is used as an injection to reduce joint pain, increase muscle, and speed up injury repair. The treatment cycle usually involves injections administered daily over 6-12 weeks. Results vary depending on the individual.

GHK-Cu is a peptide identified in the human plasma, urine, and saliva. It is a copper peptide that has evidence suggesting that they are critical to normal body functioning. A lot of research shows that GHK-Cu has benefits, including wound healing, attracting immune cells, antioxidant and anti-inflammatory properties, and other functions like stimulating collagen production.

Studies show that GHK-Cu levels decrease as you age. Because it has antioxidant properties, it reduces oxidative stress and free radicals. GHK-Cu has been demonstrated in clinical studies to tighten loose skin and increase elasticity, density, and firmness. It is used in cosmetic products to reduce fine lines and wrinkles, and provides many other benefits related to skin rejuvenation.

PT-141 (also known as Bremelanotide) was developed from the peptide hormone Melanotan II, which induced darkening of skin pigments. In studies, volunteers noted that it caused sexual arousal in women, as well as arousal and spontaneous erections in men. It is a revolutionary treatment that acts on the nervous system as opposed to the vascular system (as medications like Viagra and Cialis do). PT-141 directly increases sexual desire in both men and women. Its direct nervous stimulation makes it a safer option for people with heart conditions when medications that effect the heart may be contraindicated.

Semaglutide is a glucagon like peptide(GLP-1) analog. GLP-1 is a hormone produced in the small intestine that stimulates insulin secretion and inhibits glucagon secretion, thereby lowering blood sugar. Semaglutide reduces appetite, improves control of eating, and reduces food cravings in addition to improving glycemic control. Dosing is by injection once weekly.

CJC 1295 is a synthetic peptide that was found to enhance the performance of athletes. It increases protein synthesis and insulin-like growth factor, which results in muscle growth. It also improves recovery time, and studies show it improves sleep quality and cognitive function.

Ipamorelin directly stimulates the pituitary gland to produce growth hormone. The reason these are combined is because the onset of Ipamorelin is fast and CJC-1295 acts slower and lasts longer. Dosing is usually by injection daily or daily with a skip day every 2-3 days. Results begin with improved sleep and recovery times in the first several weeks, with skin improvement and body composition changes by week six.

NAD+ is a coenzyme found in all living cells. It is crucial for the functioning of the mitochondria, the cellular powerhouse. The problem is that levels significantly decline as we get older. Poorly functioning mitochondria are thought to contribute to many age-related problems.

Mitochondria help a class of proteins that regulate the life of the cell, called sirtuins (SIRT). NAD+ increases SIRT1, which stimulates new mitochondria formation and life extension, and SIRT6, which maintains the length of the telomeres associated with longevity. It is also crucial for DNA repair.

Oral supplements of NAD+ are broken down in the gut, so IV infusions are the most effective way to boost NAD+. Subcutaneous injections are also an option. Results tend to occur fast with increased mental clarity being the most pronounced symptom.

Of all peptides, MOTS-c is unique in that it is a signaling peptide that comes from the mitochondria’s DNA, not the cell’s DNA. It fights weight gain and normalizes metabolism in a manner similar to exercise. It has been shown to improve the body’s sensitivity to insulin, reduces fat, increases energy, and reduces appetite.

Most people have a hard time losing weight as they age. The extra weight leads to an increase in the NNMT enzyme, making it harder to lose weight and more likely that you’ll accumulate more fat. It is a vicious cycle. For this reason, reducing NNMT can be crucial to weight loss. 5-Amino-1MQ works as an NNMT inhibitor and can significantly reduce body weight. White adipose mass decreases adipose temperature and lowers plasma total cholesterol levels. 5-amino-1MQ may be a valuable peptide for weight loss, because it enables your body to burn fat for energy. What’s more, because of this, it helps maintain muscle mass.

Sermorelin is what is known as an HGH stimulator. HGH is responsible for stimulating growth, healing, and the renewal of all the cells in your body. Sermorelin actually supports pituitary function (rather than inhibiting it) and encourages the natural production of human growth hormone. It has also shown to be more natural in the way it is released into the body, more closely mimicking the body’s natural, gradual release of growth hormone. This is considered much safer than the consistently high levels seen in patients who opt for HGH injections. Sermorelin therapy enables patients to obtain all of the benefits of HGH therapy, without the associated risks.

Selank belongs to a class of molecules called synthetic peptides. It was made by combining the sequence of a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is a peptide closely related to the immune function. It occurs naturally and makes up one part of the natural antibody IgG. The peptide Selank has been labeled as an “anti-anxiety” peptide and has also shown improvement in learning, memory, cognition, depression, weakness, and overall energy. While most prescription drugs cause many unwanted side effects, studies have shown this peptide to have no negative side effects or risk of addiction. Selank has shown the ability to reduce anxiety and increase serotonin levels. This peptide is used as a nasal spray. This is because it will be digested by the stomach if taken orally. Inhaling it is more effective for delivery to the bloodstream and into the brain.

Exenatide, a glucagon-like peptide-1 receptor (GLP-1R) agonist, improves glycemic control in patients with type 2 diabetes through multiple mechanisms of action: increased glucose-dependent insulin secretion, attenuated postprandial glucagon secretion, slowed gastric emptying, and increased satiety. Exenatide therapy is associated with weight loss and improvement in cardiovascular risk factors, including blood pressure and serum lipid profiles.

Semax is a peptide developed in Russia to boost cognition, and treat strokes and brain damage. As a synthetic form of the adrenocorticotropic hormone, it acts directly on the brain. It helps with memory, improves symptoms of ADHD, and helps with blood circulation in the brain. As an added benefit, it helps reduce pain by preventing the breakdown to enkephalins, which are the neurotransmitters that dull pain. It can be given via nasal spray, and effects can be immediate.